所有分类
产品编号 | bs-1223P |
英文名称 | Aggrecan Peptide |
中文名称 | 软骨蛋白聚糖/可聚蛋白多糖 多肽 |
别 名 | Aggrecan; Aggrecan core protein; Cartilage-specific proteoglycan core protein; CSPCP; Chondroitin sulfate proteoglycan core protein 1; Chondroitin sulfate proteoglycan 1; Aggrecan core protein 2; AGC1; CSPG1; MSK16; PGCA_HUMAN. |
性 状 | Lyophilized powder |
多肽活性 | 多肽 |
产品来源 | 合成 |
分 类 | |
偶联蛋白 | |
纯化方法 | HPLC |
产品应用 | Blocking Peptide of The bs-1223R Antibody |
保存条件 | Store at -20 °C for one year. |
产品介绍 | bs-1223P is one synthetic peptide derived from human ACAN. Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS. |